Side Effects To HGH

To Avoid Side Effects to HGH Only Inject Normal Physiologcal Levels

The Norditropin Injection Pen is one of the best ways to avoid the side effects to HGH. Its state-of-the-art mechanical delivery of your dose eliminates mistakes. The dose is provided to you by the doctor and it is easily dialed into the pen. 

Side Effects to HGH Norditropin Pen
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Overview of Side Effects to HGH

Side Effects to HGH Injections are Reduced with Norditropin HGH Pen

Growth hormone (GH) is a protein hormone produced by the pituitary gland that promotes growth, cell regeneration, and repair in humans and other animals. In recent years, synthetic growth hormone has become available as a prescription medication for people with certain medical conditions. While growth hormone therapy can be beneficial, it also comes with potential side effects that patients should be aware of. In this article, we’ll provide an overview of growth hormone side effects and discuss ways to minimize their impact.

Common Side Effects of Growth Hormone Therapy

  1. Swelling or puffiness: Growth hormone therapy can cause swelling or puffiness in different parts of the body, including the hands, feet, and face.

  2. Joint and muscle pain: Some patients may experience joint and muscle pain as a result of growth hormone therapy.

  3. Headaches: Headaches are a common side effect of growth hormone therapy. They can range from mild to severe and can occur frequently or infrequently.

  4. Increased insulin resistance: Growth hormone therapy can lead to an increase in insulin resistance, which can contribute to the development of type 2 diabetes.

  5. High cholesterol levels: Growth hormone therapy can cause an increase in LDL (“bad”) cholesterol levels and a decrease in HDL (“good”) cholesterol levels.

  6. Edema: Edema is a condition in which excess fluid accumulates in the tissues, causing swelling. Growth hormone therapy can cause edema in different parts of the body, including the ankles and feet.

  7. Carpal tunnel syndrome: Growth hormone therapy can cause carpal tunnel syndrome, which is a condition in which the median nerve that runs from the forearm to the hand becomes compressed.

  8. Gynecomastia: Gynecomastia is a condition in which male breast tissue becomes enlarged. It can occur as a side effect of growth hormone therapy.

How to Best Avoid Growth Hormone Side Effects to HGH

  1. Start with the Norditropin HGH Pen. It helps you get the correct dose thus preventing injecting too much growth hormone. 
  2. Then begin with a low dose: If you’re just starting growth hormone therapy, your doctor will likely start you on a low dose and gradually increase it over time. This can help minimize the risk of side effects.

  3. Monitor your blood sugar levels: If you’re at risk for developing type 2 diabetes, your doctor may recommend monitoring your blood sugar levels while you’re on growth hormone therapy. This can help identify any changes early on and prevent the development of diabetes.

  4. Monitor your cholesterol levels: Regular monitoring of your cholesterol levels can help identify any changes and allow your doctor to make adjustments to your medication or lifestyle as needed.

  5. Exercise regularly: Regular exercise can help minimize the risk of joint and muscle pain associated with growth hormone therapy. It can also help improve insulin sensitivity and cholesterol levels.

  6. Maintain a healthy weight: Maintaining a healthy weight can help reduce the risk of developing type 2 diabetes and can also help minimize joint pain.

  7. Get enough sleep: Getting enough sleep is important for overall health and can help reduce the risk of headaches and other side effects associated with growth hormone therapy.

  8. Follow a healthy diet: Eating a healthy diet can help improve insulin sensitivity and cholesterol levels, which can help minimize the risk of side effects associated with growth hormone therapy.


Growth hormone therapy can be beneficial for individuals with sub-optimal levels, but it also comes with potential side effects. By following the tips outlined above, patients can help minimize their risk of experiencing these side effects and maximize the benefits of growth hormone therapy. As always, it’s important to work closely with your doctor to monitor your progress and make any necessary adjustments to your treatment plan.

Side Effects to HGH are rare. 

Rare Side Effects to HGH?

The side effects to HGH injections are minimal when taking your treatment as prescribed by your doctor. The key is to properly inject the correct dose prescribed. 

Some of the more common side effects are:

  • Carpal tunnel syndrome.
  • Joint and muscle pain.
  • Increased insulin resistance – which can be mitigated by a common medication called metformin.

More severe side effects are very rare but are possible which is why you must follow your healthcare provider’s instructions. 

  • Risk of Type 2 diabetes.
  • Increased risk of certain cancers.
  • Decreased risk of certain cancers as defined by its reduction in the cancer biomarker PD1 as described by Stanford and UCLA researchers in the TRIIM Anti-Aging Research Study

Metformin to Reduce Side Effects to HGH and Insulin Resistance

For individuals concerned of the side effect of developing insulin resistance, discuss with your doctor the use of Metformin. Metformin is a first-line treatment for type 2 diabetics. It is also being studied as an anti-aging drug. The medication may offer dual benefits. That is, reducing a side effect of insulin resistance and perhaps benefiting longevity markers. 

To learn more about Metformin and Anti-Aging, see our Metformin Anti-Aging page

Do Side Effects to HGH Injections Go Away?

Side effects to HGH are rare and most are managed easily by your doctor. As long as your blood labs are kept up to date and you feel okay, your risk of HGH side effects is very low. 

All medications have side effects if they are abused. Assuming your dose of HGH is set correctly it will be unlikely for you to feel stiffness in the joints or carpel tunnel syndrome. And if you are eating well and managing your weight, there is little concern about developing insulin resistance. Again, this is why your doctor needs updated lab work at least every 6 months. 

You may want to consider metformin. Review the paragram on metformin for more information. 

HGH Injections - Prevent Side Effects to HGH

Growth Hormone Injection Device that helps Avoid Side Effects to HGH

The Norditropin Pen offers a dial up helps prevent dose error thus causing side effects.

What is Somatropin / HGH?

Somatropin is a recombinant human growth hormone. It is available by prescription only. It is taken by injection. HGH Gels and HGH sprays are not real somatropin and don’t have the same physiological effect on the body. 

Human Growth hormone is prescribed to help children grow taller. It is also prescribed for adults to treat conditions of low growth hormone production.

Norditropin 10MG/30IU is one of the more common growth hormones prescribed. Its popularity is due to the convenience of use. Norditropin sells between $1,300 – $1,500 for one injection pen. One injection pen can support some protocols for approximately 20 days at 1.5 IU. Injections are generally prescribed in adults for deficiencies for 4-5 days per week. 

Get HGH Price Details and Download PDF

Norditropin HGH Price Updates | Anti-Age Costa Rica

You will get the dosing guide and updated pricing for real HGH (Norditropin HGH), plus any discounts offered. 

Domestic HGH Prive Versus Costa Rica Price

Find the latest price information on HGH (Somatropin) here. The HGH for sale price review of somatropin in the USA is updated monthly. The table provides the average somatropin for sale price taken from the top 10 USA cities. Included are price comparisons with international rates for the same medication in The typical medical examination and laboratory fees are listed also. This page provides prospective patients with comprehensive price information. The top 10 cities are ranked in order of population beginning with New York, Los Angeles, and Chicago…, and concluding with San Jose, California.

HGH - USA Price $570.00 initial exams $1,295.00 monthly
HGH - Mexico Price $550.00 initial exams $550.00 monthly (Out of Stock)
HGH - Costa Rica Price $550.00 initial exams $550.00 monthly

Note: Prices are close estimates based on typical patient averages. It is approximated using a Norditropin 10MG/30IU growth hormone injection pen.

Minor rate adjustments may occur depending on your prescription and dosage. The typical patient will see a rate very close to those mentioned in this table.

Norditropin HGH is FDA approved in the United States for growth hormone replacement therapy in children and adults. 

Initial programs of 90-days minimum are generally recommended to observe measurable improvements in body composition, fat loss, energy levels, and exercise intensity. 

HGH is not FDA approved for anti-aging therapy. However, the following two research studies may be of interest to those looking for improving aging biomarkers.

Reversal of epigenetic aging and immunosenescent trends in
humans, Aging Cell. 

Effects of human growth hormone in men over 60 years old, New England Journal of Medicine.

Please help us share - Side Effects to HGH with Others


So many Americans remain unaware that brand name prescription medications are one-half or one-third the price in other countries. More recently, the state of Utah just passed ‘Right to Shop’ Legislation so workers can go to Tijuana Mexico for prescription medications. 

When you share this content, you help us help others save!

Traveling with Prescriptions?

Only get HGH therapy from authorized licensed healthcare professionals. Our protocols are developed based on standardized bioidentical hormone replacement protocols. 

HGH San Diego Costs - Tijuana Mexico Costs
Norditropin HGH NordiFlex Pen $550 USD in Costa Rica & Mexico

Last Updated February 2023

Top 10 USA Cities For Sale Price and Locations

As you browse the prices throughout the United States, remember that this same pen is $550.00 USD in Costa Rica and Mexico. Same medication by the same manufacturer. 

Typically a Somatropin cash-based prescription will sell in New York City between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

ShopRite Pharmacy $1,243.23
1 Garet Pl
Commack, NY

Typically a Somatropin cash-based prescription will sell in Los Angeles between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Ralphs Pharmacy $1,280.75
645 W 9th St
Los Angeles, CA

Typically a Somatropin cash-based prescription will sell in Chicago between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Costco Pharmacy $1,243.23
1430 S Ashland Ave
Chicago, IL

Typically a Somatropin cash-based prescription will sell in Houston between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

HEB Grocery Pharmacy $1,265.53
3663 Washington Ave Ste 100
Houston, TX

Typically a Somatropin cash-based prescription will sell in Phoenix between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Frys Pharmacy $1,280.75
100 E Jefferson St
Phoenix, AZ

Typically a Somatropin cash-based prescription will sell in Philidelphia between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Acme Markets Pharmacy $1,288.48
180 W Girard Ave
Philadelphia, PA

Typically a Somatropin cash-based prescription will sell in San Antonio between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

HEB Pharmacy $1,280.75
108 N Rosillo
San Antonio, TX

Typically a Somatropin cash-based prescription will sell in San Diego between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

ShopRite Pharmacy $1,280.75
1 Garet Pl
Commack, NY

Typically a Somatropin cash-based prescription will sell in Dallas between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Benzer Pharmacy $1,243.23
600 N Pearl St Ste H201
Dallas, TX

Typically a Somatropin cash-based prescription will sell in San Jose between $1,300 USD to over $2,000 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Safeway Pharmacy $1,288.48
1300 W San Carlos St
San Jose, CA

Somatropin for Sale Rate in Tijuana Mexico

HGH San Diego Costs - Tijuana Mexico Costs
Norditropin HGH NordiFlex Pen

Typically a Somatropin cash-based prescription will sell at Anti-Aging and Wellness ranges between $550 USD per month. 

 For Norditropin HGH NordiFlex 10MG Injection Pen

Anti-Aging and Wellness TJ $550.00

Typically a Somatropin cash-based prescription will sell at Anti-Aging and Wellness is approximately $550 USD per month. 

 For Norditropin HGH Nordilet 10MG Injection Pen

Anti-Aging and Wellness  Clinic $550.00

Sale Price Comparison

LA Area Pricing Vs. Anti-Aging and Wellness

Rite Aid RX Norditropin HGH $1,292.22

Anti-Aging and Wellness HGH $550.00

How Much Does Growth Hormone Cost in Costa Rica and Mexico?

The rate for a Norditropin HGH pen which contains 10MG and 30IU of treatment is $550. For many undergoing HGH therapy as part of an HGH deficiency and age management program in the United States, this is one-third the amount these patients are paying just a few minutes across the border. It is the exact same medication by the same pharmaceutical companies. 

The reason HGH is more expensive in the United States than in Mexico and Costa Rica is due to global pricing models set by large pharmaceutical companies. That’s it. The medications are the same and from the same manufacturers.  

How Does One Qualify for HGH Therapy?

There are many factors that go into determining if HGH therapy is a good option for adult patients. Unfortunately for those living in the USA, it’s more determined by the size of the person’s pocketbook. Many among the rich and famous are already using HGH for their own medical lifestyle choices. Some of these people include Suzanne Somers, Sylvester Stallone, and billionaire tech entrepreneur Peter Thiel

To qualify for a deficiency, patients must undergo comprehensive blood testing, a medical examination, and submit a detailed medical intake questionnaire. 

If you have the following side-effects, you may be a good candidate to get yourself testing.


Should I Take Metformin on HGH Therapy?

Metformin is the first line of treatment for adult-onset diabetes and is used in some cases for prediabetics. Some doctors may use it as a weight-loss medication. It is currently being studied for anti-aging purposes by leading scientists. See <TAMES Clinical Trials> study. 

Famous Harvard anti-aging researcher David Sinclair (Comments on Tom Bilyeu YouTube channel) and others are taking metformin for age management, not as a diabetic medication. 

Dr. Sinclair also supplements with NAD+ (NMN) for its benefits related to longevity and mitochondrial wellness.  

Anti-Aging and epigenetics (Understanding Epigenetics NIH). Recently a small research study was published regarding key aging biomarkers being reversed by 2 years or more after taking HGH and Metformin over 12 months <Aging Cell – Reversal of Aging>, [Aging Cell – Reversal of Aging pdf]. 

We do not prescribe Metformin for anti-aging purposes. However, we do follow evidence-based research related to the standard American diet and its influence on glycemic variability and proper glucose control. 

Let’s face it, approximately 70% of the population is overweight or obese. Most of these patients are potentially near diabetic (prediabetic) or will be within a matter of 10-15 years.

Reference this one Japanese study on forecasting type II diabetes 10 years in advance. Other research going all the way back to the 1970s suggests the same thing. Detection of Diabetes In Situ, by Dr. Kraft, MD.

We approach health and wellness through integrative medicine. Our physicians pay close attention to various blood biomarkers which may indicate poor glucose control. In those instances, we will assess each individual’s health, and if they should undergo a strict lifestyle modification program. In some cases, Metformin may be a good option for the patient.  

US-based' Cost Alternatives for Residents in Top 10 US Cities

If you are a current patient of US-based, Healthgains, NuMale, or another popular US-based age management treatment center and paying over $1,000 monthly for your HGH therapy, then it’s time to consider your alternatives. 

We can match and/or improve upon your existing protocols for less. No matter how affluent you are, no one wants to pay two or three times the price for treatment for the same medications.  

US-based’ Cost Alternatives – Benefits with our programs:

  1. Our initial consultation fee is $550, US-based’ is around $4,000 or more for HGH programs and testing.
  2. No unnecessary and expensive VO2 Max (See our VO2 Max VLOG) testing which can be estimated for most people with a low-end Fitbit or alternative smartwatch. If you are not a world-class endurance athlete, VO2 max may not be all that much use to you, as many other biomarkers can help predict cardiovascular health.
  3. No risky or expensive DEXA scans. These emit low energy radioactive waves into the body that may damage your mitochondria at the cellular level. Mitochondria are the powerhouse of energy metabolism which is what we are trying to improve upon in the first place. If you’re not at risk for bone demineralization, avoid these.
  4. Most of our patients on a typical age management program which includes HGH will invest around $550 per month for their treatment. HGH prescription programs in the USA for the same amount of treatment will start at approximately $1,295 per month.
  5. Name brand HGH like Norditropin. Norditropin comes premixed and in the famous Norditropin self-contained HGH Injection Pen. No mixing required. No refrigeration required for up to 21 days under certain conditions.

Is it Legal for Me to Take HGH?

Our HGH programs are prescribed by licensed physicians in the US and abroad who use best practices for evaluating, prescribing and treating patients with HGH.

Our priority is on patient safety and optimal wellness. We do comprehensive blood testing, complete medical intake, and clinical examinations. Once it is determined between the patient and their doctor that growth hormone therapy can be prescribed, we continue to monitor, re-examine, and adjust protocols to ensure patient safety, benefits and treatment efficacy.

Is HGH for Sale? Can I Buy HGH?

No, absolutely not. HGH is available by prescription only. It is very rare for USA-based insurance companies to authorize HGH prescriptions. So, each patient will pay for HGH therapy as an out-of-pocket medical expense. 

We strongly discourage patients from buying HGH on the street or from an international online pharmacy. Much of the growth hormone bought in this manner may be counterfeit or not high-quality pharmaceutical grade HGH like Norditropin, Saizen or others. 

HGH is a very delicate hormone and it is difficult to produce. For years leading big-pharma laboratories were only capable of producing a close version of HGH in the lab. The earlier type of HGH was 192 amino acid structure. True HGH is a 191 amino acid protein that can, in some cases, lead to antibody response and the treatment will lose its effectiveness.

We only prescribe 100% bioidentical growth hormone(s) from the leading pharmaceutical companies. These include companies like:

Growth Hormone and Anti-Aging

For years HGH was touted as an anti-aging medication, but it is not an anti-aging drug. HGH may provide certain growth effects that help offset many side-effects of aging, like sarcopenia (muscle wasting), body composition, and blood lipids, among others. 

Okay, now the good news. A new but small 2019 HGH / Metformin research study published in the Aging Cell journal has been making headlines in the news. Probably not since the landmark HGH study conducted by Dr. Rudman in 1990, has a single growth hormone study received so much buzz. 

Let’s first step back in time to the Dr. Rudman study released in 1990. This study was one of the first studies done on a limited number of adult men and published in the prestigous New England Journal of Medicine. This is about the same time when famous actors and actresses like Sylvester Stallone and Suzanne Somers began publically announcing their use of human growth hormone and other bioidentical hormones for age management purposes. Essentially the Rudman study determined the following <Download Dr. Rudman HGH Research Study pdf>:

    • Men 61-81 years old injected HGH daily over a 6-month period.
    • No major adjustment to lifestyle was enforced.
    • Improved lean muscle mass of approximately 8.8% was measured.
    • The reduction of body fat was reduced by almost 15%, while their overall weight remained the same. 
    • Bone density increased by 1.7%.
    • Skin thickness increased by over 7%.

For Dr. Rudman New England Journal of Medicine HGH Study <Download Dr. Rudman HGH Research Study pdf>.

Now, researchers in California have observed key aging markers by reversing age by almost 3 years.

These therapies and protocols are not proven nor have they been evaluated by the FDA. This information is scientific in nature. Always seek the advice of your physician before considering if this type of therapy is something you should consider for yourself. 

Is HGH from Mexico & Costa Rica Safe?

When HGH is prescribed by one of our doctors in the US, Costa Rica, or Mexico, the medication is safe. It is the same brand that is sold in the USA. All our HGH prescriptions come from major pharmaceutical companies. They come from registered pharmacies or distributors in their respective countries. 

How do I get Started?

It’s best to fill in our contact form or call us direct. This enables us to discuss your specific situation in more detail and determine the best treatment center for your care.

Before any treatment program is recommended, patients must complete a medical history questionnaire,  receive comprehensive blood testing, and meet with the physician. Blood testing can be done at our treatment centers or at a local Quest Diagnostic diagnostic location.

Cost Benefits of the HGH with us

Let’s face it, for many HGH is too expensive. Unless you are a Hollywood A-lister or billionaire tech entrepreneur, it isn’t a viable option unless you seek treatment abroad.

We operate age management treatment centers in the US and in other countries. This enables us to treat at far lower rates than other age management groups like US-based. We can offer HGH therapies at our international centers for 60% less, for those willing to work with one of our US trained international doctors and treatment centers. 

Lifestyle Recommendations while on Therapy

Avoid fad diets and processed foods. If fat loss is needed, we prefer to use scientific approaches like intermittent fasting, fasting-mimicking (FMD), or intermittent ketogenic dieting, which have all been proven to various degrees using the scientific method. Much research is being done in this area at many leading Universities, and we’ve found it to be a great approach for fat loss for many people. It is not for everyone though, so our medical practitioners will review each individual case.

We like to see patients get into healthy nutritional ketosis periodically to support the beneficial role of cell apoptosis and autophagy. Some patients who are overweight may prefer doing a diet program in connection with their hormone replacement therapy. The two methods together form a very powerful integrative approach to overall health and wellness.  

  • We discourage smoking and heavy drinking. For those who wish to continue to drink socially, we recommend refraining from high-sugar alcoholic beverages with added sweetened mixers or that are high in carbohydrates. This enlists high blood sugar and high insulin response, which immediately slows or stops entirely fat loss. Red wine and clear alcohols generally have less impact on blood sugars, and this will help improve body composition sooner. 
  • Eat whole foods and avoid processed foods. Whole foods, for the most part, digest slower and have a less negative impact on increasing blood sugars and insulin response. Fruits should be limited to some degree. When consuming fruits, it is recommended to eat fruits like berries and avocados. Berries are sweet in taste but have less negative impact on blood sugar and insulin response. 
  • Avoid fruit juices and other types of sugary beverages. Many of these so-called healthy juices are packed with sugary-carbohydrates that elevate blood sugars and insulin response, making fat loss more difficult.

Get HGH Price Details and Download PDF

Norditropin HGH Price Updates | Anti-Age Costa Rica

You will get the dosing guide and updated pricing for real HGH (Norditropin HGH), plus any discounts offered. 

Anti-Aging and Wellness Center by Age Metrics Medical S. A.

The Anti-Aging & Weight Loss Center by Age Metrics Medical is part of the original Anti-Aging and Wellness Medical Clinic (Est. 2013). The clinic is one of the longest-running most successful anti-aging centers in all of Latin America for Weight Loss and Anti-Aging and Wellness therapies. Our doctors are US board-certified in Anti-Aging and Regenerative Medicine by the A4M.

Side Effects to HGH Clinic

Board-Certified Anti-Aging & Regenerative Medicine A4M

Providing evidence-based Anti-Aging, Weight Loss, and Regenerative therapies. All of our treatment programs are supervised medically by Dr. Jeff Ugalde, MD. He has been part of the Anti-Aging and Wellness team since 2014 serving as its Medical Director. He is the most experienced doctor in Anti-Aging Medicine in Costa Rica. He has over 20 years of experience as a physician and is US board certified by the American Academy of Anti-Aging and Regenerative Medicine. 

Side Effects to HGH Doctor
Dr. Jeff Ugalde, M.D.

Medical Experience & Certifications

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Side Effects to HGH